Infectious Disease Models

Infectious diseases remain the leading cause of morbidity and mortality worldwide. In vivo mouse models facilitate evaluation of the effectiveness of vaccines and/or therapeutic regimens as well as their potential to compromise immune cell responses to infection. These established models enable researchers to screen high numbers of candidates at a relatively low cost using a large number of reagents and gene-knockout strains. TICRO has successfully established mouse models of infectious disease for the purpose of better understanding the host-pathogen interaction. Moreover, TICRO has over 20 pathogens implicated in human health and disease that can be studied in a variety of inbred, congenic, transgenic and mutant mouse strains.



  • Influenza virus
  • Lymphocytic choriomeningitis virus
  • Murine Gamma Herpes virus


  • Mycobacterium tuberculosis
  • Streptococcus pneumonia
  • Pseudomonas aeruginosa
  • Klebsiella pneumonia
  • Campylobacter jejuni
  • Citrobacter rodentium
  • Eschericha coli
  • Listeria monocytogenes
  • Salmonella
  • Sphingomonas
  • Yersinia enterocolitica
  • Yersinia pseudotuberculosis
  • Borrelia burgdorferi
  • Staphylococcus aureus


  • Heligomosomoides polygyrus
  • Toxoplasma gondii
  • Trichuris muris
For detailed information on specific organisms, please contact us:
(518) 891-3080