Infectious Disease Models

TICRO utilizes a robust, small animal platform comprised of mice, ferrets, and hamsters, to provide compelling in vivo research solutions.

Our established preclinical infectious disease models enable researchers to screen high numbers of candidates at relatively low cost using a large number of reagents, diagnostic assays, and a variety of translational model species.

TICRO has successfully established and validated these models of infectious disease for the purpose of better understanding host-pathogen interactions and to evaluate candidate therapeutics. Moreover, TICRO maintains a library of > 20 pathogens implicated in human health and encompassing diseases relevant to the study of respiratory, enteric, ESKAPE, and parasitic infections. TICRO has the expertise, experience, and facilities to work with pathogens that require specialized housing and biosecurity requirements. These pathogens can be studied in a variety of inbred, congenic, transgenic and mutant mouse strains as well as in ferrets (e.g. influenza) and hamsters (e.g. SARS-CoV-2).

A list of our current offering of model pathogens is provided below. Please contact us for additional information or regarding the need for model development.